Memoray management issue in sap abap stack

Dear Friend,

I am facing some memory  management issue in my sap production server. we are using ecc 6.0 EHP4 with 48 gb ram and total 150 gb swap space size.

we are using windows server 2008 r2 server. how to set the best parameter size. My current parameter are

Generic key table buffer TABL
zcsa/table_buffer_area 30000000 Byte Size of generic key table buffer
zcsa/db_max_buftab     5000          Max. number of buffered objects

abap/buffersize 300000 kB   Size of program buffer

abap/pxa        shared      Program buffer mode

rsdb/ntab/entrycount 20000

With Regards

Pradeep Kumar